Working with the computer late at night can really hurt the eyes. It burns most of the time and looking at all the details in documents and spreadsheets can really be confusing when the monitor is glaring at you.
Then I came across F.lux.
I had been using the software for a year now and it has been good to my eyes. Since it removes that Eerie Blue Glow from your screen, it actually improves sleep the moment you hit the sack.
I highly recommend it for people who work at night.
Download here.